Helminthic therapy and neurological disorders
Neurological disorders are any disorders of the nervous system.
See
Epilepsy[edit | edit source]
The Th17/Treg balance is essential for immune homeostasis in the brain. While Th17 cells are proinflammatory and neurotoxic, Treg (CD4+Foxp3+) lymphocytes exert immunosuppressive effects that limit excessive inflammation and maintain tolerance. In epileptic conditions, this balance shifts toward Th17 predominance, as reflected by decreased Treg frequency and function, reduced FoxP3 expression, and upregulated RORγt-mediated Th17 differentiation.[1]
Helminths improve the Th17/Tregs ratio and could therefore have an beneficial effect.
See also
- 2025 Aug 22 Probiotics and the Gut-Brain Axis: Emerging Therapeutic Strategies for Epilepsy and Depression Comorbidity -- Full text | PDF
- 2024 Nov 22 Ketogenic Diet and Neuroinflammation: Implications for Neuroimmunometabolism and Therapeutic Approaches to Refractory Epilepsy -- Full text | PDF
- 2024 Feb 15 Peripheral blood regulatory B and T cells are decreased in patients with focal epilepsy
Long Covid[edit | edit source]
See Helminthic therapy and COVID-19
Neurofibromatosis type I[edit | edit source]
Neurofibromatosis type I (NF-1), or von Recklinghausen syndrome, is a neurodevelopmental disorder many individuals with which also experience neuropsychiatric manifestations.
Peripheral nerve injury[edit | edit source]
- 2025 Nov 11 Schistosoma japonicum peptide SJMHE1 promotes peripheral nerve regeneration via macrophage migrasome-derived miR-26b-5p targeting the PTEN/AKT axis -- Full text | Full text
Spinal cord injury[edit | edit source]
See also
- 2025 Oct 6 Neuroinflammation: targeting microglia for neuroprotection and repair after spinal cord injury -- Full text | PDF
- 2017 Feb Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury -- Full text | PDF
Stroke[edit | edit source]
See also
ILC2
- 2025 Nov 3 Brain-infiltrating ILC2s boost poststroke angiogenic initiation through α-CGRP production
- 2024 Mar Group 2 innate lymphoid cells suppress neuroinflammation and brain injury following intracerebral hemorrhage -- Full text | PDF
Foxp3+
- 2023 Apr FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation -- Full text | PDF
Microbiota-Gut-Brain Axis
- 2025 Oct 16 Molecular Mechanisms of the Microbiota-Gut-Brain Axis in the Onset and Progression of Stroke -- Full text | PDF