Helminthic therapy and bladder

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Bacterial urinary tract infections

• 2020 Dec 9 IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection

Bladder cancer

See Helminthic therapy and cancer: Bladder cancer

Bladder pain

• 2020 Jan-Dec IPSE, a parasite-derived, host immunomodulatory infiltrin protein, alleviates resiniferatoxin-induced bladder pain

Chemotherapy-induced hemorrhagic cystitis

• 2019 Jun 1 IPSE, a parasite-derived host immunomodulatory protein, is a potential therapeutic for hemorrhagic cystitis
• 2018 Aug Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis
• 2019 Feb 7 IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways

Interstitial cystitis (IC)

Interstitial cystitis (IC), is a type of bladder pain syndrome (BPS) featuring chronic pain of unknown cause affecting the bladder and pelvic floor.

If interstitial cystitis is an autoimmune disease, as many authorities appear to think that it is, it might be expected to respond to helminthic therapy, and there are a few individuals with this condition who have reported experiencing benefits after introducing helminths. Included amongst these individuals are several people with a number of overlapping conditions that include interstitial cystitis.

One self-treater posted the following hopeful note:

On a side note, my interstitial cystitis has improved to almost 100% remission since start of hookworm therapy, but this might also be the result the entocort. Either way, I'm hopeful this improvement will remain after I taper in the next couple weeks. (Posted to the now defunct Yahoo Helminthic Therapy forum.)

Another self-treater posted this comment:

I stopped IC flaring after I started xyrem. While on xyrem I started HT and since then only a few short flares in the 4 pregnancies I've had since starting HT. So it seems to be keeping me in remission. But I've also been pregnant and/or breastfeeding so that may be helping too. [1]

See also

• How DMSO Treats "Incurable" Autoimmune and Contractile Disorders. This article contains references to interstitial cystitis, including, near the end of the article, details of how to administer DMSO in the treatment of this disorder.

The reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat or prevent chronic inflammation, autoimmune disease and other immune-related disorders, including allergy.

The reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat or prevent chronic inflammation, autoimmune disease and other immune-related disorders, including allergy.

An intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. Wikipedia:Helminths

Someone who treats their own disease or condition without medical assistance.

A helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin.

The reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat or prevent chronic inflammation, autoimmune disease and other immune-related disorders, including allergy.

helminthic therapy