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Human helminth care manual: Difference between revisions

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* ✅ [https://en.wikipedia.org/wiki/Cromoglicic_acid Cromoglicic acid] (cromolyn, cromoglycate or cromoglicate, sodium cromoglicate [Nalcrom] or cromolyn sodium, plus Gastrocrom and Intercron) <br>This is a mast cell stabiliser which prevents the release of histamine from mast cells and is used to treat some allergic conditions. One hookworm host has taken 8x100mg capsules of Nalcrom daily for periods of up to 10 days without any adverse effect on her colony. [https://www.facebook.com/groups/htsupport/permalink/952539741468648/?comment_id=953466358042653&comment_tracking=%7B%22tn%22:%22R1%22%7D]
* ✅ [https://en.wikipedia.org/wiki/Cromoglicic_acid Cromoglicic acid] (cromolyn, cromoglycate or cromoglicate, sodium cromoglicate [Nalcrom] or cromolyn sodium, plus Gastrocrom and Intercron) <br>This is a mast cell stabiliser which prevents the release of histamine from mast cells and is used to treat some allergic conditions. One hookworm host has taken 8x100mg capsules of Nalcrom daily for periods of up to 10 days without any adverse effect on her colony. [https://www.facebook.com/groups/htsupport/permalink/952539741468648/?comment_id=953466358042653&comment_tracking=%7B%22tn%22:%22R1%22%7D]


* ⚡ [https://en.wikipedia.org/wiki/Doxylamine Doxylamine] (Dozile, Restavit, Valocordin-Doxylamine and Vomentin) <br>One hookworm host believes that an unexpected return of gut symptoms and dry skin may have been caused by taking a quarter of a tablet of this firstgeneration antihistamine every night for a couple of weeks. [https://www.facebook.com/groups/htsupport/permalink/927991007256855/?comment_id=1007272959328659&comment_tracking=%7B%22tn%22:%22R%22%7D]
* ⚡ [https://en.wikipedia.org/wiki/Doxylamine Doxylamine] (Dozile, Restavit, Valocordin-Doxylamine and Vomentin) <br>One hookworm host believes that an unexpected return of gut symptoms and dry skin may have been caused by taking a quarter of a tablet of this first-generation antihistamine every night for a couple of weeks. [https://www.facebook.com/groups/htsupport/permalink/927991007256855/?comment_id=1007272959328659&comment_tracking=%7B%22tn%22:%22R%22%7D]


* ⚡ [http://en.wikipedia.org/wiki/Ketotifen Ketotifen] - This antihistamine and mast cell stabilizer, which has similar effects to cromoglicic acid (see separate listing), is sold under a large variety of trade names[https://www.drugs.com/international/ketotifen.html] that include Allerban, Allergan, Bentifen, Ketasma, Mastifen, Zaditen and Zylofen. In a small in vitro test, one hookworm self-treater found that exposing a sample of Necator americanus larvae to Naziden left them “a bit lethargic but alive” [https://www.facebook.com/groups/htsupport/permalink/1037890422933579/?comment_id=1039541612768460&reply_comment_id=1041766029212685&comment_tracking=%7B%22tn%22:%22R8%22%7D] and that they were still alive the next day. [https://www.facebook.com/groups/htsupport/permalink/1037890422933579/?comment_id=1039541612768460&reply_comment_id=1042321262490495&comment_tracking=%7B%22tn%22:%22R3%22%7D] However, effects in vivo don’t always correspond with those observed in a petri dish, and ketotifen is a piperazine-related substance so it may have an adverse effect on human helminths in vivo in at least some users.
* ⚡ [http://en.wikipedia.org/wiki/Ketotifen Ketotifen] - This antihistamine and mast cell stabilizer, which has similar effects to cromoglicic acid (see separate listing), is sold under a large variety of trade names[https://www.drugs.com/international/ketotifen.html] that include Allerban, Allergan, Bentifen, Ketasma, Mastifen, Zaditen and Zylofen. In a small in vitro test, one hookworm self-treater found that exposing a sample of Necator americanus larvae to Naziden left them “a bit lethargic but alive” [https://www.facebook.com/groups/htsupport/permalink/1037890422933579/?comment_id=1039541612768460&reply_comment_id=1041766029212685&comment_tracking=%7B%22tn%22:%22R8%22%7D] and that they were still alive the next day. [https://www.facebook.com/groups/htsupport/permalink/1037890422933579/?comment_id=1039541612768460&reply_comment_id=1042321262490495&comment_tracking=%7B%22tn%22:%22R3%22%7D] However, effects in vivo don’t always correspond with those observed in a petri dish, and ketotifen is a piperazine-related substance so it may have an adverse effect on human helminths in vivo in at least some users.
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