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Helminthic therapy and COVID-19: Difference between revisions

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Added a question and answer about the possibility of material from COVID vaccines entering worms and future hosts.
(→‎The emerging science: Added a citation.)
m (Added a question and answer about the possibility of material from COVID vaccines entering worms and future hosts.)
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There have been several reports of Strongyloides stercoralis hyperinfection in COVID-19 patients treated with corticosteroids. [https://pubmed.ncbi.nlm.nih.gov/34446397/] [https://pubmed.ncbi.nlm.nih.gov/32830642/] [https://pubmed.ncbi.nlm.nih.gov/34127256/] [https://pubmed.ncbi.nlm.nih.gov/34150517/] [https://pubmed.ncbi.nlm.nih.gov/32910321/] However, while this particular nematode species is of special concern in immunosuppressed persons due to the possibility of potentially life-threatening systemic hyperinfection, [https://www.ncbi.nlm.nih.gov/pubmed/25774935] [https://www.ncbi.nlm.nih.gov/pubmed/30898993] TSO, TTO, HDC and NA do not present the same risk due to their inability to multiply within a host.
There have been several reports of Strongyloides stercoralis hyperinfection in COVID-19 patients treated with corticosteroids. [https://pubmed.ncbi.nlm.nih.gov/34446397/] [https://pubmed.ncbi.nlm.nih.gov/32830642/] [https://pubmed.ncbi.nlm.nih.gov/34127256/] [https://pubmed.ncbi.nlm.nih.gov/34150517/] [https://pubmed.ncbi.nlm.nih.gov/32910321/] However, while this particular nematode species is of special concern in immunosuppressed persons due to the possibility of potentially life-threatening systemic hyperinfection, [https://www.ncbi.nlm.nih.gov/pubmed/25774935] [https://www.ncbi.nlm.nih.gov/pubmed/30898993] TSO, TTO, HDC and NA do not present the same risk due to their inability to multiply within a host.
=== Can the mRNA and spike proteins from COVID vaccines pass into hookworm larvae? ===
This question, which was asked in the Helminthic Therapy Support group, [https://www.facebook.com/groups/htsupport/posts/5427440317311879/?comment_id=5427968547259056] appeared to have arisen as a result of concern about the possibility of the vaccine mRNA or reverse transcribed spike protein DNA persisting in the cells of human vaccinees - a fiercely debated issue. The concern in the mind of the NA self-treater who asked the question was perhaps about whether any spike protein genetic material in the blood ingested by a hookworm might then be integrated into that worm’s genome, and passed, first, to the worm’s progeny, and then to their next human host, where it might be integrated into that host’s genome.
This possibility is thought to be vanishingly improbable because, firstly, the blood ingested by an adult hookworm will be broken down by the digestive enzymes and microbiota of the worm’s gut. And, secondly, because, even if an intact strand of the spike protein gene were to survive the digestive process, it would need to be absorbed, and then - the toughest challenge of all - would need to get into the worm’s ovary or testis, and into the chromosome of a germ cell. And this exceedingly improbable journey would need to be followed by another, in which a gene in the new generation of hookworms would need to be transmitted to the next human host.
This is therefore not something that hookworm self-treaters need to worry about. [https://www.facebook.com/groups/htsupport/posts/5427440317311879?comment_id=5430907446965166]
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